Shanghai Medicilon Inc.

  Dry eye, also known as dry eye disease (DED), dry eye syndrome, and keratoconjunctivitis sicca (KCS), is a multifactorial disease of the ocular surface. Dry eye is characterized by a loss of homeostasis of the tear film, and accompanied by ocular symptoms, in which tear film instability and hyperosmolarity, ocular surface inflammation and damage, and neurosensory abnormalities play etiologic roles. Dry eyes affect a significant number of people, the cause of dry eye is multifactorial, in which ocular, anatomical and systemic factors play crucial roles. Prompt treatment significantly improves long-term quality of life, provides relief from dry eyes, and improves outcomes. Model of Dry Eye Syndrome Healthy rats were selected and given subcutaneous injections of scopolamine four times daily for 4 weeks and placed in dry room. Schemer‘s test and corneal conjunctiva stained with tiger red and fluorescein were performed before administration and on the 1st, 3rd, 5th, 7th, 14th, and 28th da