Shanghai Medicilon Inc.

     A new technique for constructing   chiral drug molecules , whose structural complexity allows them to have mirror-image, “left-handed” and “right-handed” forms, has been developed at The Scripps Research Institute (TSRI). Unlike most previous chirality-inducing reactions, the novel method requires only starting chemicals that are inexpensive and widely available.   Medicilon’s drug discovery platform serves the early stages of new drug research and development projects, and is committed to helping customers obtain pharmaceutical substitute compounds through high-quality and efficient chemical and biological research services. Medicilon utilizes asymmetric synthesis technology, chiral decomposition and chiral separation technology to improve the efficiency of chiral drug research and development, which has advanced the chiral drugs of many leading pharmaceutical company to the next stage.             ❖    ...

  Chiral drugs   refer to drugs that contain chiral centers (including chiral carbon, chiral nitrogen, chiral sulfur, etc.) in their molecular structure. In January 1992, the FDA promulgated the “Development of Stereoisomer Drugs” technical research guidelines, giving guidance on the work that needs to be done in the research of stereoisomer drugs. In December 2006, the CFDA issued the “Technical Guidelines for the Quality Control of Chiral Drugs”, which provided detailed guidance on the research work that needs to be carried out in the   synthesis process , structural confirmation and quality control research of chiral drugs, and indicated for the research of chiral drugs. Up the direction. As a special kind of chemical drugs, chiral drugs should not only follow the “Guiding Principles for the Research of Chemical Drug Preparation Processes”, but also combine the introduction of chiral centers to establish appropriate process control indicators for monitoring. The config...