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目前显示的是标签为“Chemistry Services”的博文

Nine Development Trends of Chemical Synthetic Drugs

  As an important part of drug research and development, chemically synthesized drugs are still the subject of new drug research and development for major pharmaceutical companies in the world today. The production of chemical drugs is inseparable from three stages: raw material pretreatment, chemical reaction and product refinement. Chemical drugs can be inorganic minerals or   synthetic organic compounds , effective monomers extracted from natural drugs, or antibiotics obtained by fermentation. In the future, the development of chemically synthesized drugs presents the following development trends: Discover new lead compounds from medicinal plants, modify their structures, and invent new drugs Chinese herbal medicine has been used for thousands of years, and very valuable experience has been obtained in the treatment of various diseases including tumors. Abundant Chinese herbal medicine resources also provide an important material basis for the search for new anti-cancer dru...

Medicilon FTE services & FFS services - flexible and efficient cooperation model

  With the rapid development of the global pharmaceutical market and the division of labor in the pharmaceutical industry, the chain is becoming more and more refined, making specialized outsourcing in the pharmaceutical industry an important strategic choice for pharmaceutical companies. In the early stages of new drug development, FTE (Full-time equivalent) is often used by drug discovery companies to synthesize the required structural fragments and/or potential candidate compounds to accelerate the drug screening process. Medicilon provides comprehensive  chemistry research services  covering all stages of your project requirements, and customers can cooperate with us through the FFS (Fee for Service) or FTE (Full-time Equivalent Service) models. Contact Us Full-Time Employee (FTE) Medicilon has a dedicated R&D and project management team. According to customer requirements, it can configure different proportions of R&D staff with different levels of Ph.D., M.S...

Analytical Chemistry

Well-designed and well-validated analytical methodology is critical to data integrity and central to our approach. We work closely with clients to ensure that our methodology will yield accurate results. Meanwhile, our precise quality systems ensure that all the facilities, equipment, methods, practices, records, and controls are tightly compliant with our regulations, study protocols, and standard operating procedures. Supporting chemistry FTE, custom synthesis and scale up synthesis High throughput purification and analysis capability Structure and purity determination Impurity characterization Chiral purity 2 on-site NMR, one equipped with auto-sampler 3 LC-MS, equipped auto-sampler Water content &residual solvent Certification of analysis (COA) Find out more " www.medicilon.com "

Library Synthesis

We utilize medicinal chemistry and computational chemistry to design and synthesize drug-like templates and libraries of compounds to increase our clients' compound collections. The annual capacity of library production is more than 100,000 compounds. Design and synthesis of focused libraries Solution phase parallel synthesis Hands on experience in solid phase synthesis Automated purification capability Find out more " www.medicilon.com "

Process &Scale up Synthesis

We have sucessfully supplied one client 6 kgs of product with eight synthetic steps within a very short period, including reaction optimization. High quality products in multi-kilogram quantities Process development, Route scouting and optimization On-site analytical support Product delivered with COA Medicilon offers integrated drug discovery services -- Chemistry, Biology & Preclinical Services

Custom Synthesis

Medicilon has synthesized over 10,000 individual compounds from gram to kilogram quantities, and many compounds are synthesized with more than ten synthetic steps. The overall synthesis success rate is over 95%. High quality products from mg to kg scale Reagents, intermediates, building blocks, and scaffolds Preparation of API or reference standards Development of synthetic routes for impurities and metabolites   On-site analytical support Product delivered with COA Medicilon offers integrated drug discovery services -- Chemistry, Biology & Preclinical Services