Protein kinases are a group of enzymes with the basic biochemical function of phosphorylation of other proteins. Protein kinases represent one of the most important classes of cellular proteins. As the principle components of cell signal transduction pathways, the activity of kinases often controls the activities of “effector” proteins, which in turn affect the profiles of cellular gene expression. Kinase signaling pathways play a primary role in regulating cell proliferation, cell metabolism and cell death. Research has shown that changes in protein kinase activity within a cell can lead to several disease states, most notably cancer. With this knowledge base, scientists have been investigating the ability of drugs to block various protein kinases as a cancer therapy. In addition to their involvement in cancer, protein kinases are implicated in diabetes, inflammation and neurological development and degeneration. Protein Kinase Assay Medicilon is offering kinas...
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