As an important organ of the body, the eyes are responsible for perceiving the external world. The eyes complete about 90% of the information obtained by human sensory organs from the outside world. The structure of the eye is delicate, and even a slight injury may cause structural changes, resulting in decreased or complete loss of visual function, resulting in immeasurable losses. [1] The eye has unique anatomical and physiological properties that limit the delivery of drugs to target ocular tissues/sites. Most ophthalmic drugs are administered topically in the conjunctival sac, most commonly in the form of eye drops. Affected by various physiological barriers, the ocular bioavailability of eye drops is extremely low, generally less than 5%. [4] Today, recent advances in the fields of pharmacy, biotechnology, and materials science are facilitating the development of novel ophthalmic dosage forms that provide sustained drug delivery, reduce dosing frequency, and increase the ocular bi...
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