Analytical Chemistry and Its Application Scope

Do you know the Analytical Chemistry and Its Application Scope? Analytical Chemistry is the branches of chemistry. The main task of Analytical Chemistry is to identify the chemical composition (elements, ions, functional groups, or compounds) of the substance, to determine the content of the relevant components of the substance and the structure of the substance (chemical structure, crystal structure, spatial distribution), the existence of the form (valence state, coordination state, crystalline state) and its relationship with the nature of the material, mainly for structural analysis, morphological analysis, energy analysis.

Field of application of Analytical Chemistry: Analytical chemistry has a very high practical value, made an important contribution to the material civilization of mankind, widely used in geological survey, mineral exploration, metallurgy, chemical industry, energy, agriculture, medicine, clinical laboratory, environmental protection, commodity inspection, Archaeological analysis, forensic criminal investigation and other fields.

Analytical methods should be simple, not only field work (such as geological survey, chemical prospecting, environmental monitoring, soil testing, etc.) but needs simple and effective chemical analysis methods and indoor routine analysis work as well.

analytical testing labs

Because the method is simple and the steps are small without compromising the required accuracy and precision, this means saving time, manpower and expense. For example, the gold shop to buy gold jewelry, it is in the test stone slabs (scientific name is stripes), and then from the color of the stripes to identify the fineness of gold. This striping method is still used in mineral identification.

Of course, this method is less than the fire test method or atomic absorption spectrometry accurate, but has been able to achieve the purpose of identification of gold. Another example, the urine of urine can be measured with a special enzyme-containing test paper, from the color of the test paper to estimate the amount of sugar content; the method is simple and evens the patient. On the other hand, atomic absorption spectrometry can also indirectly measure the amount of sugar in the urine sample, but because it is not economical and not been used.

Chemical Analytical Center of Medicilon provides general analysis and purification services for the clients. Our analytical chemists have rich experience, proficient skills to solve problems, which are highly appreciated by clients in chenical tests

Analytical Chemistry Services Including:

Featured Services – Impurity Analysis

❖Impurity Isolation by Pre-HPLC
❖Impurity Identification by 1D/2D NMR、LCMS、EA、HRMS、IR、UV et al
❖Isolation and Identification of Degradation Byproduct of API
❖Q-NMR Analysis
❖IND Package Preparation

Development and Validation of Analytical Methods (Complying with guidelines of CP, USP, EMA, ICH et al)

❖Methods of Purity and Assay
❖Methods of Residue Solvents
❖Methods of Chiral Purity
❖Methods of Heavy Metal

General Analytical Chemistry Services

❖NMR 1D、2D（H-NMR、C-NMR、P-NMR、F-NMR、HSQC、HMBC、COSY、NOESY, et al）
❖LC-MS Analysis(Liquid Chromatography-Mass Spectrometry)
❖HPLC Analysis (including ELSD)
❖Chiral HPLC Analysis
❖General Testing (ROI、LOD、Cl-、SO42-、mp、HM、Specific Rotation、Water Content, et al ）

Email : marketing@medicilon.com

Tel : +44 1223 981 792 (Europe)

+82 (0)70-8269-5849 (South Korea)

08044216898 (Japan)

+86 021 58591500 (China)

Website: https://www.medicilon.com

Custom Synthesis

Medicilon has synthesized over 10,000 individual compounds from gram to kilogram quantities, and many compounds are synthesized with more than ten synthetic steps. The overall synthesis success rate is over 95%. High quality products from mg to kg scale Reagents, intermediates, building blocks, and scaffolds Preparation of API or reference standards Development of synthetic routes for impurities and metabolites On-site analytical support Product delivered with COA Medicilon offers integrated drug discovery services -- Chemistry, Biology & Preclinical Services

阅读全文

In Vitro Enzyme Activity Assay

Kinases play extensive and important roles in signal transduction and co-ordination of complex functions. Currently, about 300 kinase inhibitors have been approved for marketing, among which receptor tyrosine kinase (RTK) inhibitors are the main ones. Medicilon provides high-quality kinase profile screening and has one-stop kinase research services from assay development, high-throughput screening to selectivity analysis. In addition, Medicilon provides many other enzyme activity screens. Wide Variety Provides 200+ in vitro enzymatic detection methods; 100+ kinases, including CTK, RTK, AGC, CMGC and other kinase families as well as important common mutations Project Flexibility Various types of plates for screening, such as 96 and 384; Multiple flexible kinase profiles, including TK kinase family, CDK kinase family, etc., to meet different customer customization needs. Various Methods Fluorescence detection; Chemiluminescence detection; Absorbance detection LanthaScr...

阅读全文

Pharmacokinetics Services

Pharmacokinetics Services Our pharmacokinetics department offers the clients a broad spectrum of high quality of services in the areas of in vitro ADME, in vivo pharmacokinetics and bioanalysis services, ranging from small molecules to large molecules, such as protein and antibody. The animal species involved in our services are non-human primate, canine, mice, rat, rabbit and hamster. Meanwhile, non-human primate experimental platform and isotope platform for protein/antibody are certified by the Shanghai government. Preclinical Pharmacokinetics Method development and validation (GLP,Non-GLP) Bioanalysis Pharmacokinetics (Tumor bearing rodents, Bioavailability, Crossover studies, Cassette (N in 1) dosing and analysis, effects of gender on pharmacokinetics, BBB penetration ) Stability in vehicles and plasma Drug interaction studies In vitro metabolic stability CYP 450 inhibition Plasma protein binding studies Distribution studies Excretion studies Prediction an...

阅读全文

Shanghai Medicilon Inc.

搜索此博客