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In Vitro Enzyme Activity Assay

 Kinases play extensive and important roles in signal transduction and co-ordination of complex functions. Currently, about 300 kinase inhibitors have been approved for marketing, among which receptor tyrosine kinase (RTK) inhibitors are the main ones. Medicilon provides high-quality kinase profile screening and has one-stop kinase research services from assay development, high-throughput screening to selectivity analysis. In addition, Medicilon provides many other enzyme activity screens.

  • Wide Variety
    Provides 200+ in vitro enzymatic detection methods;100+ kinases, including CTK, RTK, AGC, CMGC and other kinase families as well as important common mutations
    In Vitro Enzyme Activity Assay Service.jpg
  • Project Flexibility
    Various types of plates for screening, such as 96 and 384;Multiple flexible kinase profiles, including TK kinase family, CDK kinase family, etc., to meet different customer customization needs.
  • Various Methods
    Fluorescence detection;Chemiluminescence detection;Absorbance detectionLanthaScreen/AlphaScreen;Z‘-LYTE,HTRFTR-FRET/FP;Kinase-Glo;ADP-Glo kinase assay, etc.
  • Fast Delivery
    Provides compounds to be tested, 2-5 mg each, Medicilon will arrange corresponding screening and detection services, and finally provide a professional analysis report;Screening cycle: 1-2 weeks, reporting cycle: 1-3 working days (the specific time depends on the experimental content).
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Custom Synthesis

Medicilon has synthesized over 10,000 individual compounds from gram to kilogram quantities, and many compounds are synthesized with more than ten synthetic steps. The overall synthesis success rate is over 95%. High quality products from mg to kg scale Reagents, intermediates, building blocks, and scaffolds Preparation of API or reference standards Development of synthetic routes for impurities and metabolites   On-site analytical support Product delivered with COA Medicilon offers integrated drug discovery services -- Chemistry, Biology & Preclinical Services
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