跳至主要内容

In Vitro Enzyme Activity Assay

 Kinases play extensive and important roles in signal transduction and co-ordination of complex functions. Currently, about 300 kinase inhibitors have been approved for marketing, among which receptor tyrosine kinase (RTK) inhibitors are the main ones. Medicilon provides high-quality kinase profile screening and has one-stop kinase research services from assay development, high-throughput screening to selectivity analysis. In addition, Medicilon provides many other enzyme activity screens.

  • Wide Variety
    Provides 200+ in vitro enzymatic detection methods;100+ kinases, including CTK, RTK, AGC, CMGC and other kinase families as well as important common mutations
    In Vitro Enzyme Activity Assay Service.jpg
  • Project Flexibility
    Various types of plates for screening, such as 96 and 384;Multiple flexible kinase profiles, including TK kinase family, CDK kinase family, etc., to meet different customer customization needs.
  • Various Methods
    Fluorescence detection;Chemiluminescence detection;Absorbance detectionLanthaScreen/AlphaScreen;Z‘-LYTE,HTRFTR-FRET/FP;Kinase-Glo;ADP-Glo kinase assay, etc.
  • Fast Delivery
    Provides compounds to be tested, 2-5 mg each, Medicilon will arrange corresponding screening and detection services, and finally provide a professional analysis report;Screening cycle: 1-2 weeks, reporting cycle: 1-3 working days (the specific time depends on the experimental content).
标签：

评论

发表评论

此博客中的热门博文

Fluorescence Probes Synthesis

Medicilon's fluorescent probes and labeling platforms can provide fluorescent probe design and synthesis services for scientific institutions, drug R&D companies, and other customers. Design and synthesis steps Fluorescent probes are tools used to detect, measure and analyze biomolecules, cells and tissues. They achieve these purposes by emitting and receiving fluorescent signals. Medicilon can complete the design and synthesis of fluorescent probes for biomolecules. Selection of target molecules and determination of target. Selection of fluorescent dyes. Design of molecular structure. Synthesize probe molecules. Testing the properties of probe molecules. Custom synthesis Medicilon's fluorescent probes and labeling platforms can provide fluorescent probe design and synthesis services for scientific institutions, drug R&D companies, and other customers. After years of development, Medicilon's fluorescent probes and labeling platforms have accumulated rich experience...
发表评论
阅读全文

Custom Synthesis

Medicilon has synthesized over 10,000 individual compounds from gram to kilogram quantities, and many compounds are synthesized with more than ten synthetic steps. The overall synthesis success rate is over 95%. High quality products from mg to kg scale Reagents, intermediates, building blocks, and scaffolds Preparation of API or reference standards Development of synthetic routes for impurities and metabolites   On-site analytical support Product delivered with COA Medicilon offers integrated drug discovery services -- Chemistry, Biology & Preclinical Services
发表评论
阅读全文