Medicilon was selected into the SSE Science and Technology Innovation Board 100 Index, R&D intensity and revenue growth have been recognized

On August 7, 2023, the Shanghai Stock Exchange officially launched the SSE Science and Technology Innovation Board 100 Index, a new index added to the STAR Market. The SSE Science and Technology Innovation Board 100 Index selects 100 stocks with medium market capitalization and good liquidity from the STAR Market as index samples, and together with the SSE Science and Technology Innovation Board 50 Index to constitute the SSE Science and Technology Innovation Board Scale Index Series. Shanghai Medicilon Inc. (Medicilon, stock code "688202.SH") was selected as one of the SSE Science and Technology Innovation Board 100 Index.

The SSE Science and Technology Innovation Board 100 Index has distinct characteristics. Taking the latest sample as an example, the Chinese pharmaceutical industry accounts for nearly 30% of the SSE Science and Technology Innovation Board 100 Index. In terms of innovation capability and performance growth, the total investment in research and development of the SSE Science and Technology Innovation Board 100 Index sample companies in 2022 is RMB 28.9 billion, accounting for an average of 19% of operating income. The average compound annual growth rate of operating income of the sample companies in the past three years is as high as 38.9%, and the R&D intensity and revenue growth rate are both higher than the average level of the STAR market. From 2019 to 2022, Medicilon's revenue has tripled, and its net profit attributable to the parent company has increased by 5 times, and the overall development trend will continue to rise.

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Medicilon and Binhui Biopharmaceutical Have Reached a Strategic Collaboration to Jointly Draw a New Blueprint for the Development of New Biological Drugs

On March 18, Medicilon and Binhui Biopharmaceutical (Binui Bio) announced a strategic collaboration. The two parties will work together to jointly explore the possibilities in cutting-edge fields such as oncolytic viruses, nucleic acid drugs and protein drugs. Gather and Work Together to Create Advantages Facilitate the Research and Development of Oncolytic Viruses, Nucleic Acids, Proteins and Other Drugs As a one-stop biopharmaceutical comprehensive preclinical R&D service CRO, Medicilon has been developing and accumulating for 20 years, always adhering to the spirit of innovation, and has successfully constructed bi/multi-specific antibodies, ADCs , mRNA vaccines , small nucleic acid drugs , PROTAC , and CGT technical service platform that have helped 421 INDs obtain clinical approval. It is this outstanding achievement that has earned Medicilon wide recognition in the industry and laid a solid foundation f...

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The Launch Meeting was Held by Medicilon and DAC Biotech of the Contract Research on ADC Preclinical Study

Chuansha, Shanghai, Nov. 8th, 2019 — Medicilon held the launch meeting with Hangzhou DAC Biotech Co., Ltd to initiate the preclinical study of the antibody-drug-conjugate (ADC) DXC005, including the pharmacology study , DMPK study and the safety evaluation . Medicilon has previously completed integrated preclinical research on ADC drugs cooperating with DAC Biotech and other companies. Two of them has been approved by NMPA and entered Phase I clinical trials. About Hangzhou DAC Biotech Co., Ltd Hangzhou DAC Biotech, Co., Ltd was officially registered in HEDA Area, Hangzhou City, Zhejiang Province, China around the end of Year 2012, and is located nearby the bank of beautiful Qiantang River. The company focuses on developing conjugate of monoclonal antibody and small molecular cytotoxic drug, both of which are banded together with smart linkers. About Antibody-Drug-Conjugate (ADC) ADCs ...

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A Nickel-Catalyzed Reductive Alkylation of Aryl Bromides and Chlorides for Sp3-Sp2 Bond Formation

In 2012, a nickel-catalyzed reductive alkylation method of aryl bromides and chlorides was reported. Under the optimized conditions, a variety of aryl and vinyl bromides as well as active aryl chloride can be reductively coupled with alkyl bromides in high yields. The protocols were highly functional-group tolerant and the reactions were not air or moisture sensitive. The reaction showed different chemoselectivity than conventional cross-coupling reactions. Substrates bearing both anelectrophilic and nucleophilic carbon resulted in selective coupling at the electrophilic carbon (R-X) and no reaction occurred at the nucleophilic carbon (R-[M]). The 2010 Nobel Prize in Chemistry was awarded for the Pd-catalyzed cross-coupling, and in the past decade the progress in cross-coupling has not only had a significant impact on academic research but has also influenced the industrial synthetic application. The transition-metal-catalyzed union of nucleophilic organo-boronic acids with elect...

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