Shanghai Medicilon Inc.

  Kinases play extensive and important roles in signal transduction and co-ordination of complex functions. Currently, about 300 kinase inhibitors have been approved for marketing, among which receptor tyrosine kinase (RTK) inhibitors are the main ones. Medicilon provides high-quality kinase profile screening and has one-stop kinase research services from assay development, high-throughput screening to selectivity analysis. In addition, Medicilon provides many other enzyme activity screens. Wide Variety Provides 200+  in vitro  enzymatic detection methods; 100+ kinases, including CTK, RTK, AGC, CMGC and other kinase families as well as important common mutations Project Flexibility Various types of plates for screening, such as 96 and 384; Multiple flexible kinase profiles, including TK kinase family, CDK kinase family, etc., to meet different customer customization needs. Various Methods Fluorescence detection; Chemiluminescence detection; Absorbance detection LanthaScreen/AlphaScree

  Biacore 8K can detect almost all biomolecules from various organic small molecules, peptides, proteins, nucleic acids, carbohydrates, lipids, phages, viruses and cells. Biacore 8K can also be used to study the interaction network composed of different molecules, complex assembly, protein conformational changes, thermodynamic parameters of molecular binding, and post-translational modifications of proteins. Biacore 8K provides high-quality analytical data, thereby effectively solving related problems in the current life science field. Detection Indicator Biological specificity and selectivity Compound screening Concentration analysis The binding ability - affinity analysis Target molecule activity Detection Wide Variety TGF-β superfamily (TGF-β1, TGF-β2, TGF-β3); Immunoglobulin Fc receptors (Fcγ RI, FCγ RIIB, FCγ RIIIA, FcRn from different species); Immunoglobulin superfamily cell adhesion molecules (Nectin-1, Nectin-2, Nectin-3, Nectin-4); Eph receptor family (EphA1, EphA2, EphA3, E

  In vitro  biological activity detection is a mandatory item for clinical application of biological products, with high requirements for method development, personnel operation stability, and laboratory compliance management. Medicilon's cell viability assay platform can provide compliant  in vitro  cell viability detection services that meet the application requirements. Our high-level scientific research team can assist customers in participating in new drug development and exploring drug action mechanisms, while our high-throughput screening platform can help customers conduct efficient drug screening. Empowering new drug development Wide variety Medicilon offers over  400  kinds of cell models, providing detection services and functional assay services for various signal pathways. Various Methods Cell viability assays Reporter gene assays TR-FRET FACS Radioactive assays mRNA and protein expression level detection Sample provision Customers only need to provide compounds of th

  Strong Immune System It is a solid “Shield” for human health Immunity is the bodies’ own defense mechanism.  It is the human body’s self-protection ability to identify and eliminate any foreign matter (virus, bacteria, etc.) that invades from the outside, deal with aging, damaged, dead, and degenerated own cells, as well as identify and deal with mutant cells and virus-infected cells in the body, thereby maintaining the health of the human body. The book “The Autoimmune Fix” mentions: 95% of human diseases are caused by low immunity. Immunity is increased by 30%, cancer incidence and infection rates are reduced by 50%, and people are 10 years younger. This immune system is the solid “Shield” for human health.  Different people have different immune systems.  Age is not the only factor in the “aging” of the immune system.  Underweight or obesity, bad living habits, abnormal biochemical indicators, pregnancy and disease can all affect the immune system. Low immunity will cause symptoms