Fluorescence Probes Synthesis

Medicilon's fluorescent probes and labeling platforms can provide fluorescent probe design and synthesis services for scientific institutions, drug R&D companies, and other customers.

Design and synthesis steps

• Fluorescent probes are tools used to detect, measure and analyze biomolecules, cells and tissues. They achieve these purposes by emitting and receiving fluorescent signals. Medicilon can complete the design and synthesis of fluorescent probes for biomolecules.
  Selection of target molecules and determination of target.Selection of fluorescent dyes.Design of molecular structure.Synthesize probe molecules.Testing the properties of probe molecules.

Custom synthesis

• Medicilon's fluorescent probes and labeling platforms can provide fluorescent probe design and synthesis services for scientific institutions, drug R&D companies, and other customers. After years of development, Medicilon's fluorescent probes and labeling platforms have accumulated rich experience in the synthesis of high-quality fluorescent (phosphorescent) dyes, luminescent materials, contrast agents, and their applications in novel and classical fluorescent probes. In addition, Medicilon also supports the upstream and downstream development of fluorescent biological probes, aiming to provide customers with a complete solutions for multiple biomarker studies in-vivo (in-vitro), and provide customers with multi-field and multi-level R&D service support.

Applications

• Fluorescent probes are widely used in biomedicine, drug research and development, environmental monitoring, chemical analysis and other fields.
  Cell imaging
  Fluorescent probes can be used for live cell imaging. Through the use of fluorescent probes, fluorescent probes with different properties can be used to monitor the imaging cell status of different organelles and metabolic processes. This can be applied in monitoring important biochemical processes such as cell apoptosis and reactive oxygen species generation.
  Drug screening
  Fluorescent probes can be used for protein analysis, such as protein inhibition, activation, binding, etc. The function of the protein can be monitored by observing changes in fluorescence intensity to determine whether the drug interacts with the proteins, providing a basis for further drug development.
  Drug development
  Fluorescent probes are also widely used in drug research and development, including drug absorption, metabolism, and pharmacodynamics. The properties of drug absorption kinetics can be interpreted by observing changes in fluorescence signals, providing support for further drug development.