跳至主要内容

The foundation stone laying of Medicilon's subsidiary Medicilon (Baoshan) was successfully held

 On September 21, 2022, Medicilon (Baoshan) Inc's, a subsidiary of Shanghai Medicilon Inc, groundbreaking ceremony was held in North Shanghai Parmaceutical Industrial Park.  This is another grand event following the opening of Medicilon (Hangzhou) on September 7.

Chunlin Chen.jpg

Medicilon (Baoshan) is located at the intersection of Panjing Road and Yueluo Road in Baoshan District, Shanghai.  The total investment of the project is RMB 1.57 billion, covering an area of 270,000 square meter, with a total construction area of over 150,000 square meters.  After the construction, Medicilon (Baoshan) will combine the most advanced technology and cutting-edge research fields of global drug research and development to establish a complete one-stop drug research and development platform with the ability to lead the new drug research and innovation, to establish different technology platform and to explore and form a higher level of scientific support for drug development and laboratory development pillars in China.

Medicilon Baoshan.jpg

About Medicilon

Medicilon is an integrated contract research organization (CRO), providing comprehensive one-step new drug R&D for pharmaceutical enterprises and scientific research institutions around the world. We provide one-stop customized R&D solutions ranging from precise drug targeting to IND filing assistance. Deeply integrate R&D experience, constantly climb the peak of R&D technology, and build an integrated innovation service platform for new drug R&D.

 

Medicilon Medicinal Chemistry Services

At Medicilon, Our medicinal chemistry team is capable of flexibly applying computer chemistry to assist compound design process. In the meantime, we apply advanced drug discovery technologies, including proteolysis-targeting chimera (PROTAC), DNA-encoded chemical library (DEL) and antibody drug conjugation (ADC). We are also proud of our rich experience in innovative design and patent strategies that complement our technologies. In addition, our responsive project management and effective communication help optimize our project delivery.

 

Medicilon Synthetic Chemistry Services

Medicilon is proud of our extensive expertise in synthetic organic chemistry. With a team of over 1200 chemists, our synthetic chemistry department is capable of the independent design of synthesis pathways and complex compound treatments, key to helping accelerate our clients' drug discovery. As we pay great attention to scientific morality, we protect our clients' intellectual property rights tirelessly and guarantee data integrity. Furthermore, our projects are always undertaken with a fundamental focus on safety and green chemistry.

 

Services

 AI supported route design and process optimization;

 Custom chemical synthesis;

 Synthesis of standards, reference compounds, and molecular probes;

 Synthesis of high-quality compounds from milligram to kilogram;

 Synthesis and resolution of chiral compounds and so on.


Innovative Drug R&D Services

AI R&D Innovation

   As the first CRO stock on the Sci-tech Innovation Board, Medicilon is one of the companies that pay attention to AI technology in the industry at the beginning.  Currently, Medicilon uses deep neural network machine learning technology to construct a BTK inhibitor drug design model.  Medicilon also commits to establishing a molecular design and screening platform for BTK inhibitor drugs, launching “CRO+AI” to accelerate the development of new drugs.

Antibody-Drug Conjugate (ADC)

Medicilon offers clients with a pool of payload drugs of various mechanisms and offers custom synthesis of payload drugs. Medicilon fully understands the complexity of ADA evaluation and offers our clients with comprehensive immunogenicity assays.

Proteolysis Targeting Chimera (PROTAC)

Medicilon gathers the popular POI ligands and multiple tissue types of E3 ligase ligands, in addition of established a linker library containing hundreds of linking molecules. Medicilon has established a complete PROTAC in vitro analysis platform.

#PROTAC #AI #drugdiscovery

评论

此博客中的热门博文

In Vitro Enzyme Activity Assay

  Kinases play extensive and important roles in signal transduction and co-ordination of complex functions. Currently, about 300 kinase inhibitors have been approved for marketing, among which receptor tyrosine kinase (RTK) inhibitors are the main ones. Medicilon provides high-quality kinase profile screening and has one-stop kinase research services from assay development, high-throughput screening to selectivity analysis. In addition, Medicilon provides many other enzyme activity screens. Wide Variety Provides 200+  in vitro  enzymatic detection methods; 100+ kinases, including CTK, RTK, AGC, CMGC and other kinase families as well as important common mutations Project Flexibility Various types of plates for screening, such as 96 and 384; Multiple flexible kinase profiles, including TK kinase family, CDK kinase family, etc., to meet different customer customization needs. Various Methods Fluorescence detection; Chemiluminescence detection; Absorbance detection LanthaScr...

Fluorescence Probes Synthesis

Medicilon's fluorescent probes and labeling platforms can provide fluorescent probe design and synthesis services for scientific institutions, drug R&D companies, and other customers. Design and synthesis steps Fluorescent probes are tools used to detect, measure and analyze biomolecules, cells and tissues. They achieve these purposes by emitting and receiving fluorescent signals. Medicilon can complete the design and synthesis of fluorescent probes for biomolecules. Selection of target molecules and determination of target. Selection of fluorescent dyes. Design of molecular structure. Synthesize probe molecules. Testing the properties of probe molecules. Custom synthesis Medicilon's fluorescent probes and labeling platforms can provide fluorescent probe design and synthesis services for scientific institutions, drug R&D companies, and other customers. After years of development, Medicilon's fluorescent probes and labeling platforms have accumulated rich experience...

Custom Synthesis

Medicilon has synthesized over 10,000 individual compounds from gram to kilogram quantities, and many compounds are synthesized with more than ten synthetic steps. The overall synthesis success rate is over 95%. High quality products from mg to kg scale Reagents, intermediates, building blocks, and scaffolds Preparation of API or reference standards Development of synthetic routes for impurities and metabolites   On-site analytical support Product delivered with COA Medicilon offers integrated drug discovery services -- Chemistry, Biology & Preclinical Services