Top 10 Global CDMO in 2022

In recent years, the global CDMO industry has maintained steady growth. In terms of revenue, Switzerland's Lonza ranks first, with sales of 5.4 billion Swiss francs in 2021, a year-on-year increase of 20%. Followed by are WuXi AppTec and WuXi Biologics, the total revenue was US$5.214 billion, a year-on-year increase of 49.83%, with nearly 45,000 total employees.

There are 9 companies with revenue of more than 1 billion US dollars. Two companies wihch from China and South Korea are on the list. The rest are European and American companies, and there is only one company Catalent in the United States. From the perspective of revenue growth, WuXi has grown by 50% year-on-year last year, far exceeding other companies.

Catalent's revenue in last year was $3.998 billion, a year-on-year increase of 29%, ranking third. In March 2013, Catalent established the 8th clinical supply center in the world and the 1st clinical supply center in China, and named its Chinese company after "Catalent".

Catalent's revenue.jpg

Swiss CDMO company, Recipharm ranked fifth. On April 11, 2022, it announced the completion of the acquisition of advanced therapy CDMO Arranta Bio and gene therapy CDMO Vibalogics, expanding the field of biopharmaceutical CDMOs. On January 10, 2021, Pharmaron announced the successful acquisition of Aesica , a subsidiary of Recipharm in Cramlington, UK, to enhance the overall strength of the small molecule CDMO service platform.

WuXi Biologics had revenue of $1.6 billion last year, and South Korea’s Samsung Biologics had revenue of $1.226 billion last year, a year-on-year increase of 34.6%. In the field of biopharmaceutical CDMOs, WuXi Biologics has the second largest market share in the world, with more than 9,800 employees.

Boehringer Ingelheim's net sales in 2021 will reach 20.6 billion euros, a year-on-year increase of 7.5%. Among them, the biopharmaceutical CDMO business achieved net sales of 917 million euros, a year-on-year increase of 9.5%. Boehringer Ingelheim covers the entire biopharmaceutical value chain, from the development and production process of producer cells (mammalian cells and microorganisms), to the production of active substances and finished pharmaceutical products, to product launch and global market supply. The company's total investment in the research pipeline is expected to exceed EUR 25 billion over the next five years.

According to WuXi Biologics' public materials, FUJIFILM Diosynth Biotechnologies' biopharmaceutical CDMO business ranks 5th, but no data has been published.

Judging from the Top 10 rankings, WuXi is likely to rank first in the future. Other Chinese company such as Asymchem, whose CDMO business revenue has reached US$730 million, will also enter the top 10 in the future.

此博客中的热门博文

What is preclinical testing?

In the process of preclinical testing of a compound or biological agent into a drug, the compound involved must go through the testing phase. First, we need to identify potential targets that can treat the disease. Then, a variety of compounds or preparations are screened out. Any compound that has shown potential as a drug for the treatment of this disease needs to be tested for toxicity before clinical testing to reduce the possibility of injury. preclinical testing What is the basis of preclinical testing? According to US Food and Drug Administration (FDA) regulations, a series of tests are required before a new drug is approved for use. In the first stage, basic research determines a hypothetical target for the treatment of a certain disease, and then screens small molecules or biological compounds to discover any substance with the potential to treat the disease. Then, a preclinical research phase followed, before which, as described above, the potential toxicity of the compou

阅读全文

Inventory of the three major in vitro pharmacokinetic research methods

The metabolic properties of a compound are an essential factor in whether or not it can be used as a drug in the clinical setting, so pharmacokinetic studies of newly synthesized compounds are required in drug development. In vitro incubation with liver microsomes, recombinant CYP450 enzyme lines, and in vitro incubation with hepatocytes are some of the more common in vitro drug metabolism methods. 1. In vitro incubation method with liver microsomes The metabolic stability and metabolic phenotypes of candidate compounds in different species of liver microsomes are good predictors of the metabolic properties of compounds in vivo. They are practical tools for evaluating candidate compounds in the pre-development phase of drug development. Liver microsomes include rat liver microsomes, human liver microsomes, canine liver microsomes, monkey liver microsomes, and mouse liver microsomes. In in vitro incubation of the liver, microsomes are the "gold standard" for in vitro d

阅读全文

Novel Parkinson’s Therapies Possible with New Mouse Model

Parkinson's disease (PD) is a neurodegenerative disorder that is marked by the accumulation of the protein, α-synuclein (αS), into clumps known as Lewy bodies, which diminish neural health. Now, researchers from Brigham and Women's Hospital (BWH) report the development of a mouse model to induce PD-like αS aggregation, leading to resting tremor and abnormal movement control. The mouse responds to L-DOPA, similarly to patients with PD. The team's study (“Abrogating Native α-Synuclein Tetramers in Mice Causes a L-DOPA-Responsive Motor Syndrome Closely Resembling Parkinson’s Disease”) on the use of this transgenic mouse model appears in Neuron . “α-Synuclein (αS) regulates vesicle exocytosis but forms insoluble deposits in PD. Developing disease-modifying therapies requires animal models that reproduce cardinal features of PD. We recently described a previously unrecognized physiological form of αS, α-helical tetramers, and showed that familial PD-causing missense mutati

阅读全文

Shanghai Medicilon Inc.

搜索此博客