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Chemical synthesized peptide drugs

 

Company Profile:

Medicilon's peptide synthesis research team is closely focused on the topic of peptide drug research and is committed to solving the core problems that limit the development and application of peptide drugs. To improve the downstream peptide drug signal transduction pathways and mechanisms of action to improve the system. Through multi-disciplinary cooperation and intersections in chemistry, biology, medicine, and pharmacy, outstanding achievements have been made in basic and applied research.

Medicilon can undertake the synthesis of special reagents, intermediates and molecular fragments, preparation of standard products, synthesis design and preparation of impurities or metabolites, synthesis of stable isotope internal standards and synthesis of tritiated compounds.

Peptide-Synthesis-Service
Chemical synthesized peptide drugs

Peptide Synthesis Service:

  • Standard chemical peptide synthesis

  • Peptide modification

  • Peptide library

  • Recombinant polypeptide expression

  • Pharmaceutical peptide synthesis

  • Structural modification

  • Nuclear magnetic structure analysis

  • function test

Peptide custom synthesis, peptide solid phase synthesis, synthetic peptide, biosynthetic peptide, genetic chemical synthesis

The development of peptide and protein drugs by chemical synthesis methods has become an effective method widely adopted. Through liquid phase synthesis, solid phase synthesis, solid/liquid synthesis combination and fragment connection, etc., many peptide and protein drugs have been successfully developed.

Peptide synthesis is the process of synthesizing polypeptides in organic chemistry. Polypeptides are organic compounds that are connected by multiple amino acids through peptide bonds. In biology, the process of synthesizing long polypeptides (proteins) is called protein biosynthesis. The synthesis of peptides is a process in which carboxyl groups (or C-terminus) and amine groups (or N-terminus) are paired with each other. Due to the possibility of unexpected reactions, protecting groups are necessary. The process of chemical peptide synthesis begins at the C-terminus and ends at the N-terminus of the peptide, whereas protein biosynthesis starts from the N-terminus and ends at the C-terminus of the polypeptide.

Contact us: 021-58591500

Email: marketing@medicilon.com

Website: www.medicilon.com

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Custom Synthesis

Medicilon has synthesized over 10,000 individual compounds from gram to kilogram quantities, and many compounds are synthesized with more than ten synthetic steps. The overall synthesis success rate is over 95%. High quality products from mg to kg scale Reagents, intermediates, building blocks, and scaffolds Preparation of API or reference standards Development of synthetic routes for impurities and metabolites   On-site analytical support Product delivered with COA Medicilon offers integrated drug discovery services -- Chemistry, Biology & Preclinical Services

In Vitro Enzyme Activity Assay

  Kinases play extensive and important roles in signal transduction and co-ordination of complex functions. Currently, about 300 kinase inhibitors have been approved for marketing, among which receptor tyrosine kinase (RTK) inhibitors are the main ones. Medicilon provides high-quality kinase profile screening and has one-stop kinase research services from assay development, high-throughput screening to selectivity analysis. In addition, Medicilon provides many other enzyme activity screens. Wide Variety Provides 200+  in vitro  enzymatic detection methods; 100+ kinases, including CTK, RTK, AGC, CMGC and other kinase families as well as important common mutations Project Flexibility Various types of plates for screening, such as 96 and 384; Multiple flexible kinase profiles, including TK kinase family, CDK kinase family, etc., to meet different customer customization needs. Various Methods Fluorescence detection; Chemiluminescence detection; Absorbance detection LanthaScr...

Pharmacokinetics Services

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