跳至主要内容

What is chemical synthesis and what are chemical synthetic drugs?

What is synthesis?

Synthesis refers to transforming a substance with a relatively simple composition into a sense with a complex design through a chemical reaction. Together with decomposition and replacement, it is also called three types of a chemical reactions.

What is chemical synthesis?

Chemical synthesis, also known as chemical synthesis, synthetic chemistry is the foundation and core of organic chemistry, inorganic chemistry, medicinal chemistry, polymer chemistry, material chemistry, and other disciplines. This course mainly introduces new concepts and new methods in the field of inorganic synthesis and organic synthesis. The organic synthesis part explicitly teaches the basic knowledge of organic synthesis and route design, modern organic synthesis methods, green synthetic chemistry, biomimetic synthesis, etc. The role of inorganic synthesis mainly teaches high-temperature synthesis, low-temperature solid-phase synthesis chemistry, hydrothermal and solvothermal synthesis, high-pressure synthesis and technology of inorganic materials, application of CVD in inorganic synthesis and material preparation, inorganic synthesis under microwave and plasma, Synthetic formulation chemistry of bit compounds, synthetic chemistry of cluster compounds, synthetic chemistry of metal-organic compounds, synthetic chemistry of porous materials, preparation chemistry of ceramic materials, preparation chemistry of inorganic membranes, synthetic crystals, etc.

Medicilon can undertake the synthesis of special reagents, intermediates and molecular fragments, preparation of standard products, synthesis design and preparation of impurities or metabolites, synthesis of stable isotope internal standards and synthesis of tritiated compounds.

Synthetic chemistry is a series of chemical reactions to obtain one or more products. Synthesis usually appears as one or more reactions manipulated by physical or chemical means. In modern laboratory applications, synthesis often implies that the entire process is reliable, reproducible, and usable across multiple laboratories.

What are chemical synthetic drugs?

Chemical synthetic drugs are chemical drugs. Generally, it refers to synthesizing a single compound using chemical synthesis. Chemically synthesized drugs have already become the "backbone product" of today's pharmaceutical industry. 80% of the top 50 best-selling drugs in the world are synthetic drugs.

Refers to the raw materials of compounds with relatively simple structures or natural products with a specific basic design, which is prepared through a series of reaction processes and has preventive, therapeutic, and diagnostic functions on the human body. With the development of organic chemistry, pharmacology, and the chemical industry, synthetic chemical drugs are developing rapidly. Their variety, output, and output value all occupy the leading position in the pharmaceutical industry. There are thousands of chemically synthesized drugs in clinical use worldwide.

Related Articles:

Chiral Drug Synthesis

Nine Development Trends of Chemical Synthetic Drugs

Six Directions of Chemical Synthesis Drug Research and Development

Chemical Synthesis

In chemistry, chemical synthesis is the process of producing desired compounds through chemical reactions. Typically, chemical reactions until the expected product are obtained in association with each point in the sequence, chemistry, and physical specific isolation, purification, and analysis are performed in multiple steps. The results must be reproduced, verified, and confirmed by other experimenters.

Chemical synthesis begins with the selection of starting materials and reagents. Various chemical reactions can be used to obtain target products. There are two ways of expressing the quantity of development: the yield expressed in mass and the yield expressed as a percentage of the theoretical amount obtained from the starting material.

In preparing complex compounds from simple compounds, multi-step operations require much time and labor until the target product is synthesized. In particular, multi-step chemical synthesis to produce natural products such as physiologically active substances or theoretically interesting organic compounds from only commercially available simple compounds is called total synthesis. Total synthesis is a purely synthetic chemical process; on the other hand, using natural products extracted from plants, animals, fungi, etc., as raw materials are called semi-synthesis.

It is awarded for outstanding organic synthesis technology. The Nobel Prize in Chemistry is awarded to those who have discovered a way to synthesize precious and complex compounds, such as Robert Burns Woodward.

Various pathways can be considered for converting compound A to product B, which are referred to as "synthetic strategies." In multistage reactions, chemical transformations are performed sequentially on a substrate, and in multicomponent responses, a single product is obtained from multiple reactants. One-pot synthesis does not isolate or purify products but chemically transforms reaction products sequentially.

评论

此博客中的热门博文

What is preclinical testing?

In the process of  preclinical testing  of a compound or biological agent into a drug, the compound involved must go through the testing phase. First, we need to identify potential targets that can treat the disease. Then, a variety of compounds or preparations are screened out. Any compound that has shown potential as a drug for the treatment of this disease needs to be tested for toxicity before clinical testing to reduce the possibility of injury. preclinical testing What is the basis of preclinical testing? According to US Food and Drug Administration (FDA) regulations, a series of tests are required before a new drug is approved for use. In the first stage, basic research determines a hypothetical target for the treatment of a certain disease, and then screens small molecules or biological compounds to discover any substance with the potential to treat the disease. Then, a  preclinical research  phase followed, before which, as described above, the potential toxicity of the compou

Inventory of the three major in vitro pharmacokinetic research methods

  The metabolic properties of a compound are an essential factor in whether or not it can be used as a drug in the clinical setting, so pharmacokinetic studies of newly synthesized compounds are required in drug development. In vitro incubation with liver microsomes, recombinant CYP450 enzyme lines, and in vitro incubation with hepatocytes are some of the more common in vitro drug metabolism methods. 1. In vitro incubation method with liver microsomes The metabolic stability and metabolic phenotypes of candidate compounds in different species of liver microsomes are good predictors of the metabolic properties of compounds in vivo. They are practical tools for evaluating candidate compounds in the pre-development phase of drug development. Liver microsomes include rat liver microsomes, human liver microsomes, canine liver microsomes, monkey liver microsomes, and mouse liver microsomes. In in vitro incubation of the liver, microsomes are the "gold standard" for in vitro d

Enzyme Activity Assay Service

  Enzymatic assay Lance Assay Alphascreen Assay Z’-LYTE Assay Adapta Assay Kinase-Glo Assay ADP-Glo Assay Ligand Binding Assay ELISA Assay HTRF Assay Enzyme activity assays  are laboratory methods for measuring enzymatic activity. They are vital for the study of enzyme kinetics and enzyme inhibition. Enzyme units : Amounts of enzymes can either be expressed as molar amounts, as with any other chemical, or measured in terms of activity, in enzyme units. Medicilon provides various  enzyme activity assays  for  kinases , phosphatases, proteinases, deacetylase, peptidase, esterase, and other enzymes. Our line of well-characterized immunoassays and biochemical kits ensures accurate and reproducible results. Enzyme is a  large category of bio-molecules  that catalyze various biological processes including metabolic processes, cellular signaling and regulation, cell division and apoptosis. Enzymatic reactions convert substrate molecules into chemically modified molecules products with high sp